About Michael Rosbash
Michael Morris Rosbash is an American geneticist and chronobiologist. Rosbash is a professor and researcher at Brandeis University and investigator at the Howard Hughes Medical Institute. Rosbash's research group cloned the Drosophila period gene in 1984 and proposed the Transcription Translation Negative Feedback Loop for circadian clocks in 1990. In 1998, they discovered the cycle gene, clock gene, and cryptochrome photoreceptor in Drosophila through the use of forward genetics, by first identifying the phenotype of a mutant and then determining the genetics behind the mutation. Rosbash was elected to the National Academy of Sciences in 2003. Along with Michael W. Young and Jeffrey C. Hall, he was awarded the 2017 Nobel Prize in Physiology or Medicine "for their discoveries of molecular mechanisms controlling the circadian rhythm". In 1984, Rosbash and Hall cloned the first Drosophila clock gene, period. Also in May 1998, Rosbash et al. discovered in Drosophila the clock gene cycle, a homolog of the mammalian bmal1 gene. In 1990, Rosbash, Hall, and Hardin discovered the role of the period gene (per) in the Drosophila' circadian oscillator.
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